発表論文

#：corresponding author

• 2010
• Higuchi, K., Iizasa, H., Sai, Y., Horieya, S., Lee, K.E., Wada, M., Deguchi, M., Nishimura, T., Wakayama, T., Tamura, A., Tsukita, S., Kose, N., Kang, Y.S., and ^#Nakashima, E. 2010. Differential expression of ezrin and CLP36 in the two layers of syncytiotrophoblast in rats. Biol Pharm Bull. 33(8):1400-6. https://doi.org/10.1248/bpb.33.1400
• 2009
• Strilić, B., Kucera, T., Eglinger, J., Hughes, M.R., McNagny, K.M., Tsukita, S., Dejana, E., Ferrara, N., and ^#Lammert, E. 2009. The molecular basis of vascular lumen formation in the developing mouse aorta. Dev Cell 17(4):505-15. https://doi.org/10.1016/j.devcel.2009.08.011
• Kunimoto, K., Nojima, H., Yamazaki, Y., Yoshikawa, T., Okanoue, T., and ^#Tsukita, S. 2009. Involvement of IQGAP3, a regulator of Ras/ERK-related cascade, in hepatocyte proliferation in mouse liver regeneration and development. J Cell Physiol. 220(3):621-31. https://doi.org/10.1002/jcp.21798
• ^#Tsukita, S., Katsuno, T., Yamazaki, Y., Umeda, K., Tamura, A., and Tsukita, S. 2009. Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function. Ann N Y Acad Sci. 1165:44-52. https://doi.org/10.1111/j.1749-6632.2009.04056.x
• ^#Adachi, M., Hamazaki, Y., Kobayashi, Y., Itoh, M., Tsukita, S., Furuse, M., and Tsukita, S. 2009. Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins. Mol Cell Biol. 29(9):2372-89. https://doi.org/10.1128/MCB.01505-08
• Minami, S., Ito, K., Honma, M., Ikebuchi, Y., Anzai, N., Kanai, Y., Nishida, T., Tsukita, S., Sekine, S., Horie, T., and ^#Suzuki, H. 2009. Posttranslational regulation of Abcc2 expression by SUMOylation system. Am J Physiol Gastrointest Liver Physiol. 296(2):G406-13. https://doi.org/10.1152/ajpgi.90309.2008
• 2008
• ^#Kubo, A., Yuba-Kubo, A., Tsukita, S., Tsukita, S., and Amagai, M. 2008. Sentan: a novel specific component of the apical structure of vertebrate motile cilia. Mol Biol Cell 19(12):5338-46. https://doi.org/10.1091/mbc.e08-07-0691
• ^#Tsukita, S., Yamazaki, Y., Katsuno, T., Tamura, A., and Tsukita, S. 2008. Tight junction-based epithelial microenvironment and cell proliferation. Oncogene. 27(55):6930-8. https://doi.org/10.1038/onc.2008.344
• ^#Ikenouchi, J., Sasaki, H., Tsukita, S., Furuse, M., and Tsukita, S. 2008. Loss of occludin affects tricellular localization of tricellulin. Mol Biol Cell. 19(11):4687-93. https://doi.org/10.1091/mbc.e08-05-0530
• Hashimoto, S., Amaya, F., Matsuyama, H., Ueno, H., Kikuchi, S., Tanaka, M., Watanabe, Y., Ebina, M., Ishizaka, A., Tsukita, S., and ^#Hashimoto, S. 2008. Dysregulation of lung injury and repair in moesin-deficient mice treated with intratracheal bleomycin. Am J Physiol Lung Cell Mol. Physiol. 295(4):L566-74. https://doi.org/10.1152/ajplung.90250.2008
• Kamiya, A., Tan, P.L., Kubo, K., Engelhard, C., Ishizuka, K., Kubo, A., Tsukita, S., Pulver, A.E., Nakajima, K., ^#Cascella, N.G., ^#Katsanis, N., and ^#Sawa, A. 2008. Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses. Arch Gen Psychiatry. 65(9):996-1006. https://doi.org/10.1001/archpsyc.65.9.996
• Okayama, T., ^#Kikuchi, S., Ochiai, T., Ikoma, H., Kubota, T., Ichikawa, D., Fujiwara, H., Okamoto, K., Sakakura, C., Sonoyama, T., Kokuba, Y., Doi, Y., Tsukita, S., Bissell, D.M., and Otsuji, E. 2008. Attenuated response to liver injury in moesin-deficient mice: impaired stellate cell migration and decreased fibrosis. Biochim Biophys Acta. 1782(9):542-8. https://doi.org/10.1016/j.bbadis.2008.06.006
• Yamazaki, Y., Umeda, K., Wada, M., Nada, S., Okada, M., Tsukita, S., and ^#Tsukita, S. 2008. ZO-1- and ZO-2-dependent integration of myosin-2 to epithelial zonula adherens. Mol Biol Cell 19(9):3801-11. https://doi.org/10.1091/mbc.e08-04-0352
• Nojima, H., Adachi, M., Matsui, T., Okawa, K., Tsukita, S., and ^#Tsukita, S. 2008. IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade. Nat Cell Biol. 10(8):971-8. https://doi.org/10.1038/ncb1757
• Katsuno, T., Umeda, K., Matsui, T., Hata, M., Tamura, A., Itoh, M., Takeuchi, K., Fujimori, T., Nabeshima, Y., Noda, T., Tsukita, S., and ^#Tsukita, S. 2008. Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells. Mol Biol Cell 19(6):2465-75. https://doi.org/10.1091/mbc.e07-12-1215
• Yamazaki, Y., Okawa, K., Yano, T., Tsukita, S., and ^#Tsukita, S. 2008. Optimized proteomic analysis on gels of cell-cell adhering junctional membrane proteins. Biochemistry. 47(19):5378-86. https://doi.org/10.1021/bi8002567
• Tamura, A., Kitano, Y., Hata, M., Katsuno, T., Moriwaki, K., Sasaki, H., Hayashi, H., Suzuki, Y., Noda, T., Furuse, M., Tsukita, S., and Tsukita, S. 2008. Megaintestine in claudin-15-deficient mice. Gastroenterology. 134(2):523-34. https://doi.org/10.1053/j.gastro.2007.11.040
• 2007
• Yamane, J., Kubo, A., Nakayama, K., Yuba-Kubo, A., Katsuno, T., Tsukita, S., and ^#Tsukita, S. 2007. Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic. Exp Cell Res. 313(16):3472-85. https://doi.org/10.1016/j.yexcr.2007.07.010
• ^#Ikenouchi, J., Umeda, K., Tsukita, S., Furuse, M., and Tsukita, S. 2007. Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization. J Cell Biol. 176(6):779-86. https://doi.org/10.1083/jcb.200612080
• Fukumoto, K., Kikuchi, S., Itoh, N., Tamura, A., Hata, M., Yamagishi, H., Tsukita, S., and ^#Tsukita, S. 2007. Effects of genetic backgrounds on hyperbilirubinemia in radixin-deficient mice due to different expression levels of Mrp3. Biochim Biophys Acta. 1772(3):298-306. https://doi.org/10.1016/j.bbadis.2006.11.005
• 2006
• Umeda, K., Ikenouchi, J., Katahira-Tayama, S., Furuse, K., Sasaki, H., Nakayama, M., Matsui, T., ^#Tsukita, S., Furuse, M., and Tsukita, S. 2006. ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation. Cell. 126(4):741-54. https://doi.org/10.1016/j.cell.2006.06.043
• Loebrich, S., Bähring, R., Katsuno, T., Tsukita, S., and ^#Kneussel, M. 2006. Activated radixin is essential for GABAA receptor alpha5 subunit anchoring at the actin cytoskeleton. EMBO J. 25(5):987-99. https://doi.org/10.1038/sj.emboj.7600995
• 2005
• Ikenouchi, J., Furuse, M., Furuse, K., Sasaki, H., Tsukita, S., and ^#Tsukita, S. 2005. Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. J Cell Biol. 171(6):939-45. https://doi.org/10.1083/jcb.200510043
• Ishikawa, H., Kubo, A., Tsukita, S., and ^#Tsukita, S. 2005. Odf2-deficient mother centrioles lack distal/subdistal appendages and the ability to generate primary cilia. Nat Cell Biol. 7(5):517-24. https://doi.org/10.1038/ncb1251
• Tamura, A., Kikuchi, S., Hata, M., Katsuno, T., Matsui, T., Hayashi, H., Suzuki, Y., Noda, T., Tsukita, S., and ^#Tsukita, S. 2005. Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells. J Cell Biol. 169(1):21-8. https://doi.org/10.1083/jcb.200410083
• 2004
• Kitajiri, S., Fukumoto, K., Hata, M., Sasaki, H., Katsuno, T., Nakagawa, T., Ito, J., Tsukita, S., and ^#Tsukita, S. 2004. Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia. J Cell Biol. 166(4):559-70. https://doi.org/10.1083/jcb.200402007
• 2003
• Hoeflich, K.P., Tsukita, S., Hicks, L., Kay, C.M., Tsukita, S., and ^#Ikura, M. 2003. Insights into a single rod-like helix in activated radixin required for membrane-cytoskeletal cross-linking. Biochemistry. 42(40):11634-41. https://doi.org/10.1021/bi0350497
• Hamada, K., Shimizu, T., Yonemura, S., Tsukita, S., Tsukita, S., and ^#Hakoshima, T. 2003. Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex. EMBO J. 22(3):502-14. https://doi.org/10.1093/emboj/cdg039
• 2002
• Kikuchi, S., Hata, M., Fukumoto, K., Yamane, Y., Matsui, T., Tamura, A., Yonemura, S., Yamagishi, H., Keppler, D., Tsukita, S., and ^#Tsukita, S. 2002. Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes. Nat Genet. 31(3):320-5. https://doi.org/10.1038/ng905
• Yonemura, S., Matsui, T., Tsukita, S., and ^#Tsukita, S. 2002. Rho-dependent and -independent activation mechanisms of ezrin/radixin/moesin proteins: an essential role for polyphosphoinositides in vivo. J Cell Sci. 115(Pt 12):2569-80.
• Shimizu, T., Seto, A., Maita, N., Hamada, K., Tsukita, S., Tsukita, S., and ^#Hakoshima, T. 2002. Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain. J Biol Chem. 277(12):10332-6. https://doi.org/10.1074/jbc.M109979200
• 2001
• Ishikawa, H., Tamura, A., Matsui, T., Sasaki, H., Hakoshima, T., Tsukita, S., and ^#Tsukita, S. 2001. Structural conversion between open and closed forms of radixin: low-angle shadowing electron microscopy. J Mol Biol. 310(5):973-8. https://doi.org/10.1006/jmbi.2001.4818
• Hamada, K., Shimizu, T., Matsui, T., Tsukita, S., Tsukita, S., and ^#Hakoshima, T. 2001. Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of the adhesion protein ICAM-2. Acta Crystallogr D Biol Crystallogr. 57(Pt 6):891-2. https://doi.org/10.1107/s0907444901005716
• Hamada, K., Seto, A., Shimizu, T., Matsui, T., Takai, Y., Tsukita, S., Tsukita, S., and ^#Hakoshima, T. 2001. Crystallization and preliminary crystallographic studies of RhoGDI in complex with the radixin FERM domain. Acta Crystallogr D Biol Crystallogr. 57(Pt 6):889-90. https://doi.org/10.1107/s090744490100556x
• Nakagawa, Y., Yamane, Y., Okanoue, T., Tsukita, S., and ^#Tsukita, S. 2001. Outer dense fiber 2 is a widespread centrosome scaffold component preferentially associated with mother centrioles: its identification from isolated centrosomes. Mol Biol Cell. 12(6):1687-97. https://doi.org/10.1091/mbc.12.6.1687